ALS
How Is ALS Diagnosed? — Page 2
The ALS exam
To receive an amyotrophic lateral sclerosis diagnosis, you’ll see a doctor who specializes in diseases of the brain and spinal cord, called a neurologist. First the doctor will ask about your family and personal medical history. Then you’ll be asked about your symptoms, including when they started.
During a neurological exam, the doctor will check for amyotrophic lateral sclerosis symptoms like these:
- Weakness, often on one side of your body
- Slurred speech and trouble moving your mouth and tongue
- Muscle twitches
- Rigid, tight muscles
- Exaggerated reflexes
- Uncontrollable laughter or crying
- Mental changes, such as trouble recognizing or remembering words
Certain criteria help doctors make an amyotrophic lateral sclerosis diagnosis. These include:
- Signs of damage to upper motor neurons in your brain
- Signs of damage to lower motor neurons in your brainstem and spinal cord
- Progression of symptoms from one part of your body to another
- Lack of evidence of other diseases that cause similar symptoms
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Updated:  
April 07, 2023
Reviewed By:  
Christopher Nystuen, MD, MBA