Rolapitant
Rolapitant Oral tablet
What is this medicine?
ROLAPITANT (roe LA pi tant) is used with other medicines to prevent nausea and vomiting caused by cancer treatment (chemotherapy).
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
liver disease
an unusual or allergic reaction to aprepitant, fosaprepitant, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Usually, you will take it one hour before your chemotherapy begins. This medicine may be taken with or without food. Do not take more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of these medicines:
thioridazine
This medicine may also interact with the following medications:
certain medicines for blood pressure, heart disease, irregular heart beat
certain medicines for depression, anxiety, or psychotic disturbances
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin, fosphenytoin
certain medicines that treat or prevent blood clots like warfarin and dabigatran
cyclosporine
dextromethorphan
digoxin
irinotecan
methotrexate
narcotic medicines for pain
pimozide
rifampin
rosuvastatin
sirolimus
topotecan
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Do not take this medicine if you already have nausea and vomiting. Ask your health care provider what to do if you already have nausea.
This medicine should not be used continuously for a long time.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
dizziness
signs of decreased red blood cells - unusually weak or tired, feeling faint or lightheaded, falls
signs and symptoms of infection like fever or chills; cough; sore throat; pain or trouble passing urine
Side effects that usually do not require medical attention (Report these to your doctor or health care professional if they continue or are bothersome.):
hiccups
loss of appetite
mouth sores
stomach pain
weight loss
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert