Penbutolol
Penbutolol Sulfate Oral tablet
What is this medicine?
PENBUTOLOL (pen BYOO toe lole) is a beta-blocker. Beta-blockers reduce the workload on the heart and help it to beat more regularly. This medicine is used to treat high blood pressure.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
diabetes
heart or vessel disease like slow heart rate, worsening heart failure, heart block, sick sinus syndrome or Raynaud's disease
kidney disease
lung or breathing disease, like asthma or emphysema
pheochromocytoma
thyroid disease
an unusual or allergic reaction to penbutolol, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking this medicine suddenly. This could lead to serious heart-related effects.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
This medicine may interact with the following medications:
certain medicines for blood pressure, heart disease, irregular heart beat
clonidine
cocaine
diuretics
ephedra, Ma Huang
ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
medicines for sleep during surgery
mefloquine
NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
reserpine
stimulant medicines like dextroamphetamine, pseudoephedrine, and others
theophylline
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine can affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
chest pain
cold or numb hands or feet
confusion
depression
fast, irregular, or slow heartbeat
feeling faint or lightheaded, falls
rapid weight gain
swollen ankles, legs
vomiting
weight loss
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
anxiety, nervous
change in sex drive or performance
diarrhea
dry skin
headache
nightmares or trouble sleeping
short term memory loss
stomach nausea, upset
unusually tired
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Close tightly and protect from light. Throw away any unused medicine after the expiration date.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert