Amlodipine; Hydrochlorothiazide; Olmesartan oral tablets
Amlodipine; Hydrochlorothiazide; Olmesartan oral tablets
What is this medicine?
AMLODIPINE; HYDROCHLOROTHIAZIDE, HCTZ; OLMESARTAN (am LOE di peen; hye droe klor oh THYE a zide; all mi SAR tan) is a combination of a calcium channel blocker, a diuretic, and an angiotensin II antagonist. This medicine is used to treat high blood pressure.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Patients over 65 years old may have a stronger reaction and need a smaller dose.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
chest pain
confusion
dark urine
diarrhea
eye pain
fast, irregular heartbeat
feeling faint or lightheaded, falls
low blood pressure
muscle cramps
redness, blistering, peeling or loosening of the skin, including inside the mouth
signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision.
stomach pain
swelling of the hands, ankles, or feet
trouble passing urine or change in the amount of urine
vomiting
weight loss
worsened gout pain
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in sex drive or performance
dizziness
headache
muscle twitching
nausea
stuffy or runny nose and sore throat
swelling of the joints
weakness
What may interact with this medicine?
alcohol
barbiturates like phenobarbital
diuretics like triamterene, spironolactone, or amiloride
lithium
medicines for blood pressure
medicines for diabetes
norepinephrine
NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
potassium salts or potassium supplements
prescription pain medicines
skeletal muscle relaxants like tubocurarine
some cholesterol lowering medicines like cholestyramine or colestipol
steroid medicines like prednisone or cortisone
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
decreased urine
diabetes
heart failure, recent heart attack, or other heart problems
if you are on a special diet, like a low salt diet
immune system problems, like lupus
kidney disease
liver disease
vomiting or diarrhea as this may cause dehydration
an unusual or allergic reaction to amlodipine, hydrochlorothiazide, sulfa drugs, olmesartan, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your doctor or health care provider for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care provider what your blood pressure should be and when you should contact him or her.
You must not get dehydrated. Ask your doctor or health care provider how much fluid you need to drink a day. Check with him or her if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care provider or pharmacist for more information.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.
Avoid salt substitutes unless you are told otherwise by your doctor or health care provider.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care provider for advice. Some ingredients may increase your blood pressure.
If you are going to have surgery or dialysis, tell your doctor or health care provider that you are taking this medicine.
Updated:  
March 13, 2020