Nifedipine
Nifedipine Oral capsule
What is this medicine?
NIFEDIPINE (nye FED i peen) is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart problems, low blood pressure, slow or irregular heartbeat
kidney disease
liver disease
previous heart attack
an unusual or allergic reaction to nifedipine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Swallow whole. Take your doses at regular intervals. Do not take your medicine more often then directed. Do not suddenly stop taking this medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
lumacaftor; ivacaftor
rifabutin
rifampin
rifapentine
St. John's Wort
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
certain medicines for blood pressure
certain medicines for diabetes
certain medicines for erectile dysfunction
certain medicines for fungal infections like ketoconazole, fluconazole, and itraconazole
certain medicines for irregular heart beat like flecainide and quinidine
certain medicines that treat or prevent blood clots like warfarin
clarithromycin
digoxin
dolasetron
erythromycin
fluoxetine
grapefruit juice
local or general anesthetics
nefazodone
orlistat
quinupristin; dalfopristin
sirolimus
stomach acid blockers like cimetidine, ranitidine, omeprazole, or pantoprazole
tacrolimus
valproic acid
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Check your blood pressure and pulse rate regularly. Ask your doctor or health care professional what your blood pressure and pulse rate should be and when you should contact him or her.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
blood in the urine
difficulty breathing
fast heartbeat, palpitations, irregular heartbeat, chest pain
redness, blistering, peeling or loosening of the skin, including inside the mouth
reduced amount of urine passed
skin rash
swelling of the legs and ankles
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
constipation
facial flushing
headache
weakness or tiredness
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Protect from light and moisture. Keep container tightly closed. Throw away any unused medicine after the expiration date.
Nifedipine Oral tablet, extended-release
What is this medicine?
NIFEDIPINE (nye FED i peen) is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat high blood pressure and chest pain caused by angina.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
heart problems, low blood pressure, slow or irregular heartbeat
kidney disease
liver disease
previous heart attack
stomach or intestine problems
an unusual or allergic reaction to nifedipine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not cut, crush or chew. Take your doses at regular intervals. Do not take your medicine more often then directed. Do not suddenly stop taking this medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
lumacaftor; ivacaftor
rifabutin
rifampin
rifapentine
St. John's Wort
This medicine may also interact with the following medications:
antiviral medicines for HIV or AIDS
certain medicines for blood pressure
certain medicines for diabetes
certain medicines for erectile dysfunction
certain medicines for fungal infections like ketoconazole, fluconazole, and itraconazole
certain medicines for irregular heart beat like flecainide and quinidine
certain medicines that treat or prevent blood clots like warfarin
clarithromycin
digoxin
dolasetron
erythromycin
fluoxetine
grapefruit juice
local or general anesthetics
nefazodone
orlistat
quinupristin; dalfopristin
sirolimus
stomach acid blockers like cimetidine, ranitidine, omeprazole, or pantoprazole
tacrolimus
valproic acid
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Check your blood pressure and pulse rate regularly. Ask your doctor or health care professional what your blood pressure and pulse rate should be and when you should contact him or her.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
If you are taking Procardia XL, you may notice the empty shell of the tablet in your stool.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
blood in the urine
difficulty breathing
fast heartbeat, palpitations, irregular heartbeat, chest pain
redness, blistering, peeling or loosening of the skin, including inside the mouth
reduced amount of urine passed
skin rash
swelling of the legs and ankles
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
constipation
facial flushing
headache
weakness or tiredness
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature below 30 degrees C (86 degrees F). Protect from moisture and humidity. Keep container tightly closed. Throw away any unused medicine after the expiration date.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert