Methylergonovine
Methylergonovine Maleate Oral tablet
What is this medicine?
METHYLERGONOVINE (meth il er goe NOE veen) is one of a group of medicines known as ergot alkaloids. It used to prevent or to treat excessive bleeding after child birth.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
high blood pressure
infection
kidney or liver disease
an unusual or allergic reaction to methylergonovine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding (this medicine may be used with care for up to 7 days without interfering with breast-feeding)
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
Do not take the missed dose. Take only the next dose according to your normal schedule. Do not take double or extra doses.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain antibiotics like clarithromycin, erythromycin, or troleandomycin
cocaine
grapefruit juice
imatinib
medicines for colds, flu, or breathing difficulties
medicines for fungal infections like itraconazole, ketoconazole, and voriconazole
medicines used to induce labor
medicines used to treat migraines like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, or zolmitriptan
midodrine
nefazodone
other ergot alkaloids like ergotamine, dihydroergotamine, ergonovine, or methysergide
some medicines for high blood pressure or chest pain
some medicines for the treatment of HIV infection or AIDS
This medicine may also interact with the following medications:
clotrimazole
fluconazole
fluoxetine
fluvoxamine
zileuton
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
Do not use tampons, have sex, or use douches until the bleeding has stopped and your doctor allows return to normal activities. Follow the instructions for your condition.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
chest pain or tightness
confusion
fast, slow, or pounding heartbeat
fever or chills
hallucinations
increased bleeding
leg or arm pain or cramps
passing tissue or large clots
seizures
swelling of hands, ankles, or feet
tingling, pain or numbness in feet or hands
unusually weak or tired
vomiting
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in taste
diarrhea
headache
nausea
stomach cramps
temporary ringing of ears
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
Keep out of the reach of children.
Store tablets at room temperature below 25 degrees C (77 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.
Methylergonovine Maleate Solution for injection
What is this medicine?
METHYLERGONOVINE (meth il er goe NOE veen) is one of a group of medicines known as ergot alkaloids. It is used to contract the uterus at the end of child birth. It is also used to prevent or to treat excessive bleeding after child birth.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
high blood pressure
infection
kidney disease
liver disease
an unusual or allergic reaction to methylergonovine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
How should I use this medicine?
This medicine is for injection into a muscle or infusion into a vein. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?
This does not apply.
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain antibiotics like clarithromycin, erythromycin, or troleandomycin
cocaine
grapefruit juice
imatinib
medicines for colds, flu, or breathing difficulties
medicines for fungal infections like itraconazole, ketoconazole, posaconazole, and voriconazole
medicines used to induce labor
medicines used to treat migraines like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, or zolmitriptan
midodrine
nefazodone
other ergot alkaloids like ergotamine, dihydroergotamine, ergonovine, or methysergide
some medicines for high blood pressure or chest pain
some medicines for the treatment of HIV infection or AIDS
This medicine may also interact with the following medications:
clotrimazole
fluconazole
fluoxetine
fluvoxamine
zileuton
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
What should I watch for while using this medicine?
See your doctor for a follow up visit as directed.
Do not use tampons, have sex, or use douches until the bleeding has stopped and your doctor allows you to return to normal activities.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
chest pain or tightness
confusion
fast, slow, or pounding heartbeat
fever or chills
hallucinations
increased bleeding
leg or arm pain or cramps
passing tissue or large clots
seizures
swelling of hands, ankles, or feet
tingling, pain or numbness in feet or hands
vomiting
unusually tired or weak
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
change in taste
diarrhea
headache
nausea
stomach cramps
temporary ringing of ears
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
Updated:  
March 21, 2017
Sources:  
U.S. FDA-approved Package Insert