Medroxyprogesterone injection [Malignancy]
Medroxyprogesterone injection [Malignancy]
What is this medicine?
MEDROXYPROGESTERONE (me DROX ee proe JES te rone) is a man-made hormone. It is used to treat the symptoms of endometrial and renal cancer.
How should I use this medicine?
This medicine is for injection into a muscle. It is given by a health care professional in a hospital or clinic setting.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breast tenderness or discharge
breathing problems
changes in vision
depression
feeling faint or lightheaded, falls
fever
pain in the abdomen, chest, groin, or leg
problems with balance, talking, walking
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
fluid retention, swelling
headache
irregular periods, spotting, or absent periods
irritation at site where injected
nausea
trouble sleeping
weight gain or loss
What may interact with this medicine?
Do not take this medicine with any of the following medications:
bosentan
This medicine may also interact with the following medications:
aminoglutethimide
antibiotics or medicines for infections, especially rifampin, rifabutin, rifapentine, and griseofulvin
aprepitant
barbiturate medicines such as phenobarbital or primidone
bexarotene
carbamazepine
medicines for seizures like ethotoin, felbamate, oxcarbazepine, phenytoin, topiramate
modafinil
St. John's wort
What if I miss a dose?
It is important not to miss your dose. Call your doctor or health care professional if you are unable to keep an appointment.
Where should I keep my medicine?
This drug is given in a hospital or clinic and will not be stored at home.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
blood vessel disease
breast cancer
history of a blood clot in the lungs or legs
liver disease
mental depression
migraine
seizures
stroke
vaginal bleeding
an unusual or allergic reaction to medroxyprogesterone, other hormones, medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine.
Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.
Updated:  
July 17, 2018