Emtricitabine; Rilpivirine; Tenofovir alafenamide oral tablet
Emtricitabine; Rilpivirine; Tenofovir alafenamide oral tablet
What is this medicine?
EMTRICITABINE; RILPIVIRINE; TENOFOVIR ALAFENAMIDE (em tri SIT uh bean; ril pi VIR een; te NOE fo veer) is 3 antiretroviral medicines in 1 tablet. It is used to treat HIV. This medicine is not a cure for HIV. This medicine can lower, but not fully prevent, the risk of spreading HIV to others.
How should I use this medicine?
Take this medicine by mouth with a glass of water and food. Follow the directions on the prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed. For your anti-HIV therapy to work as well as possible, take each dose exactly as prescribed. Do not skip doses or stop your medicine even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines. Do not stop taking except on your doctor's advice.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
dizziness
fast, irregular heartbeat
muscle pain
nausea, vomiting, unusual upset stomach or stomach pain
redness, blistering, peeling or loosening of the skin, including inside the mouth
signs and symptoms of kidney injury like trouble passing urine or change in the amount of urine
signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
signs of infection - fever or chills, cough, sore throat, pain or trouble passing urine
suicidal thoughts or other mood changes
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
abnormal dreams
diarrhea
headache
skin discoloration
trouble sleeping
weight gain around waist, back, or thinning of face, arms, legs
What may interact with this medicine?
Do not take this medicine with any of the following medications:
certain medicines for seizures like carbamazpine, oxcarbazepine, phenobarbital, phenytoin
certain medicines for stomach problems like dexlansoprazole, esomeprazole, pantoprazole, omeprazole, lansoprazole, rabeprazole
dexamethasone
lumacaftor; ivacaftor
rifampin
rifapentine
St. John's wort; Hypericum perforatum
This medicine may also interact with the following medications:
certain antibiotics like clarithromycin, erythromycin, telithromycin, rifabutin
certain medicines for fungal infections like fluconazole, voriconazole, posaconazole, ketoconazole, itraconazole
certain medicines for stomach problems like aluminum hydroxide, magnesium hydroxide, calcium carbonate, cimetidine, famotidine, nizatidine, ranitidine
certain medicines for viral infections like cidofovir, acyclovir, adefovir dipivoxil, valacyclovir, ganciclovir, valganciclovir
methadone
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store below 30 degrees C (86 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
bone problems
depression
drink alcohol-containing drinks
heart disease
kidney disease
liver disease
suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member
an unusual or allergic reaction to emtricitabine, rilpivirine, tenofovir, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your doctor or health care professional for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
If you have hepatitis B, talk to your doctor if you plan to stop this medicine. The symptoms of hepatitis B may get worse if you stop this medicine.
Updated:  
November 11, 2018