Eltrombopag tablets
Eltrombopag tablets
What is this medicine?
ELTROMBOPAG (el TROM boe pag) helps your body make more platelets. It is used to treat low platelets caused by chronic immune (idiopathic) thrombocytopenic purpura (ITP) or chronic hepatitis C infection. It is also used in patients with severe aplastic anemia.
How should I use this medicine?
Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food, or with a meal low in calcium. Avoid calcium-rich foods and antacids, aluminum, calcium, iron, magnesium, selenium, and zinc products for 2 hours before and 4 hours after taking this medicine. Take your medicine at regular intervals. Do not take it more often than directed. Do not stop taking except on your doctor's advice.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 1 year for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
changes in vision
dark urine
general ill feeling or flu-like symptoms
light-colored stools
loss of appetite
right upper belly pain
signs and symptoms of a blood clot such as breathing problems; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness or weakness of the face, arm or leg
shortness of breath, chest pain, swelling in a leg
unusual bleeding or bruising
unusually weak or tired
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
cough
diarrhea
dry mouth
headache
muscle aches
nausea
What may interact with this medicine?
antacids
bosentan
calcium supplements
certain medicines for cholesterol like atorvastatin, fluvastatin, pravastatin, rosuvastatin
certain medicines that treat or prevent blood clots like warfarin, enoxaparin, dalteparin, apixaban, dabigatran, and rivaroxaban
ezetimibe
glyburide
imatinib
irinotecan
iron supplements
lapatinib
magnesium supplements
methotrexate
mitoxantrone
multivitamins with minerals
NSAIDS, medicines for pain and inflammation, like ibuprofen or naproxen
olmesartan
omeprazole
repaglinide
rifampin
selenium
sulfasalazine
topotecan
valsartan
zinc
What if I miss a dose?
If you miss a dose, wait and take your next scheduled dose. Do not take more than 1 dose in 1 day. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
cancer
history of blood clots
eye disease, vision problems
kidney disease
liver disease
low blood counts, like low white cell, platelet, or red cell counts
have had your spleen removed
an unusual or allergic reaction to eltrombopag, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine. To receive this medicine, you, your doctor and your pharmacy must be registered in the Promacta Cares program.
Visit your prescriber or health care professional for regular checks on your progress and for the needed blood tests. It is important to keep all appointments.
Tell your doctor or health care professional right away if you have any change in your eyesight.
Updated:  
May 08, 2020