Darbepoetin Alfa injection
Darbepoetin Alfa injection
What is this medicine?
DARBEPOETIN ALFA (dar be POE e tin AL fa) helps your body make more red blood cells. It is used to treat anemia caused by chronic kidney failure and chemotherapy.
How should I use this medicine?
This medicine is for injection into a vein or under the skin. It is usually given by a health care professional in a hospital or clinic setting.
If you get this medicine at home, you will be taught how to prepare and give this medicine. Use exactly as directed. Take your medicine at regular intervals. Do not take your medicine more often than directed.
It is important that you put your used needles and syringes in a special sharps container. Do not put them in a trash can. If you do not have a sharps container, call your pharmacist or healthcare provider to get one.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. While this medicine may be used in children as young as 1 year for selected conditions, precautions do apply.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
chest pain
confusion, trouble speaking or understanding
feeling faint or lightheaded, falls
high blood pressure
muscle aches or pains
pain, swelling, warmth in the leg
rapid weight gain
severe headaches
sudden numbness or weakness of the face, arm or leg
trouble walking, dizziness, loss of balance or coordination
seizures (convulsions)
swelling of the ankles, feet, hands
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
diarrhea
fever, chills (flu-like symptoms)
headaches
nausea, vomiting
redness, stinging, or swelling at site where injected
What may interact with this medicine?
Do not take this medicine with any of the following medications:
epoetin alfa
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store in a refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Do not shake. Throw away any unused portion if using a single-dose vial. Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
blood clotting disorders or history of blood clots
cancer patient not on chemotherapy
cystic fibrosis
heart disease, such as angina, heart failure, or a history of a heart attack
hemoglobin level of 12 g/dL or greater
high blood pressure
low levels of folate, iron, or vitamin B12
seizures
an unusual or allergic reaction to darbepoetin, erythropoietin, albumin, hamster proteins, latex, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Your condition will be monitored carefully while you are receiving this medicine.
You may need blood work done while you are taking this medicine.
Updated:  
July 17, 2018