Conjugated Estrogens; Medroxyprogesterone tablets
Conjugated Estrogens; Medroxyprogesterone tablets
What is this medicine?
CONJUGATED ESTROGENS; MEDROXYPROGESTERONE (CON ju gate ed ESS troe jenz; me DROX ee proe JES te rone) is used as hormone replacement in menopausal women who still have their uterus. This medicine helps to treat hot flashes and prevent osteoporosis (weak bones).
How should I use this medicine?
Take this medicine by mouth with a drink of water. You may take this medicine with food. Follow the directions on the prescription label. You will take one tablet daily at roughly the same time each day. Do not take your medicine more often than directed.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
A patient package insert for the product will be given with each prescription and refill. Read this sheet carefully each time. The sheet may change frequently.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breast tissue changes or discharge
changes in vision
chest pain
confusion, trouble speaking or understanding
dark urine
general ill feeling or flu-like symptoms
light-colored stools
nausea, vomiting
pain, swelling, warmth in the leg
right upper belly pain
severe headaches
shortness of breath
sudden numbness or weakness of the face, arm or leg
trouble walking, dizziness, loss of balance or coordination
unusual vaginal bleeding
yellowing of the eyes or skin
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
hair loss
increased hunger or thirst
increased urination
symptoms of vaginal infection like itching, irritation or unusual discharge
unusually weak or tired
What may interact with this medicine?
barbiturates, such as phenobarbital
benzodiazepines
bosentan
bromocriptine
carbamazepine
cimetidine
cyclosporine
dantrolene
grapefruit juice
griseofulvin
hydrocortisone, cortisone, or prednisolone
isoniazid (INH)
medications for diabetes
methotrexate
mineral oil
phenytoin
raloxifene
rifabutin, rifampin, or rifapentine
tamoxifen
thyroid hormones
topiramate
tricyclic antidepressants
warfarin
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
What should I tell my health care provider before I take this medicine?
They need to know if you have any of these conditions:
blood vessel disease or blood clots
breast, cervical, endometrial, or uterine cancer
diabetes
endometriosis
fibroids
gallbladder disease
heart disease or recent heart attack
high blood cholesterol
high blood pressure
high level of calcium in the blood
hysterectomy
kidney disease
liver disease
mental depression
migraine headaches
porphyria
protein C deficiency
protein S deficiency
stroke
systemic lupus erythematosus (SLE)
tobacco smoker
vaginal bleeding
an unusual or allergic reaction to estrogens, progestiins, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding
What should I watch for while using this medicine?
Visit your health care professional for regular checks on your progress. You will need a regular breast and pelvic exam. You should also discuss the need for regular mammograms with your health care professional, and follow his or her guidelines.
This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.
If you have any reason to think you are pregnant; stop taking this medicine at once and contact your doctor or health care professional.
Tobacco smoking increases the risk of getting a blood clot or having a stroke, especially if you are more than 35 years old. You are strongly advised not to smoke.
If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.
If you are going to have elective surgery, you may need to stop taking this medicine beforehand. Consult your health care professional for advice prior to scheduling the surgery.
Updated:  
July 17, 2018